The flow of food from the mouth via the pharynx (throat), esophagus, stomach, small and large intestines, and out of the body is referred as gastrointestinal (GI) motility. Fasting (interdigestive) and postprandial (digestive) contraction patterns are two types of GI motility that changes with a meal. Contractility of the GI tract's smooth muscles, extrinsic and intrinsic neurons (motor and sensory), and certain hormones all influence GI motility. Ghrelin (GHRL) and motilin (MLN) promote hunger and GI motility in mammals and help to maintain energy homeostasis.
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